Noah Webster's New International Dictionary of the English Language

1. (v. t.) To pay no heed to; to omit to take notice of; to neglect to observe; to slight as unworthy of regard or notice; as, to disregard the admonitions of conscience.

2. (n.) The act of disregarding, or the state of being disregarded; intentional neglect; omission of notice; want of attention; slight.